A List of Antidepressants for your Unique Needs


With the help of your doctor, choosing from a list of antidepressants can be a difficult experience.

You have different side effects, mechanisms of action, and health risks. It can get confusing, really fast!

If you're already depressed, worrying about these things is the last thing you want to do.

Hopefully this list of antidepressants will give you a better idea of what antidepressant is best for you.

Weight gain from antidepressants
, fatigue, impotence, and other side effects are the are main factors on whether you will stick to your depression treatment.

The trade and generic names for antidepressants are listed for your convenience. We compare antidepressants to give you an easier time picking the best medication for you!

Legend for Antidepressant Side Effect Profiles

Very Strong Association: ++++
Strong Association: +++
Moderate Association: ++
Weak Association: +

Weak Negative Association: -
Stong Negative Association: --

Types of Antidepressants

Anti-Depressant Class Indications Effective Tired Weight Gain Sexual Sides Comments
Fluoxetine (Prozac) Selective Serotonin Reuptake Inhibitor (SSRI) Depression, Panic, GAD, Social Anxiety, OCD, Bulimia ++ + ++ +++ Low sex drive and delayed orgasm
Sertraline (Zoloft) Selective Serotonin Reuptake Inhibitor (SSRI) Depression, Panic, GAD, OCD, Bulimia ++ - ++ +++ Low sex drive and delayed orgasm
Paroxetine (Paxil) Selective Serotonin Reuptake Inhibitor (SSRI) Depression, Panic, GAD, Social Phobia OCD, Bulimia ++ + +++ +++ Low sex drive and delayed orgasm
Citalopram (Celexa) Selective Serotonin Reuptake Inhibitor (SSRI) Depression, Panic, GAD, OCD ++ + + ++ Low sex drive and delayed orgasm
Escitalopram (Lexapro) Selective Serotonin Reuptake Inhibitor (SSRI) Depression, Panic, GAD, OCD ++ + + ++ Low sex drive and delayed orgasm
Fluvoxamine (Luvox) Selective Serotonin Reuptake Inhibitor (SSRI) Depression, Panic, GAD, OCD ++ + ++ ++ Low sex drive and delayed orgasm

List of Antidepressants

Anti-Depressant Class Indications Effective Tired Weight Gain Sexual Sides Comments
Amitriptyline (Elavil) Serotonin Reuptake Inhibitor, Nor-epinephrine Reuptake Inhibitor, Histamine Antagonist (Tricyclic) Depression, Neuropathic Pain, Migraines +++ +++ +++ ++ Toxic in Overdose
Imipramine (Tofranil) Serotonin Reuptake Inhibitor, Nor-epinephrine Reuptake Inhibitor, Histamine Antagonist (Tricyclic) Depression, Childhood Enuresis +++ +++ +++ ++ Toxic in Overdose
Clomipramine (Anafranil) Serotonin Reuptake Inhibitor, Nor-epinephrine Reuptake Inhibitor (Tricyclic) Depression, OCD +++ +++ +++ ++ Toxic in Overdose
Doxepin (Sinequan) Nor-epinephrine Reuptake Inhibitor, Histamine Antagonist (Tricyclic) Depression, Anxiety, Neurosis ++ +++ +++ + Toxic in Overdose
Nortriptyline (Pamelor) Nor-epinephrine Reuptake Inhibitor (Tricyclic) Depression, Panic, Generalized Anxiety, Neuropathic Pain ++ +++ +++ + Toxic in Overdose
Desipramine (Norpramin) Nor-epinephrine Reuptake Inhibitor (Tricyclic) Depression ++ ++ ++ + Toxic in Overdose

List of Antidepressants

Anti-Depressant Class Indications Effective Tired Weight Gain Sexual Sides Comments
Venlafaxine (Effexor) Serotonin and Nor-epinephrine Reuptake Inhibitor (SNRI) Depression, Panic, GAD, OCD ++ + ++ +++ Low Sex Drive and Delayed Orgasm
Desvenlafaxine (Pristiq) Serotonin and Nor-epinephrine Reuptake Inhibitor (SNRI) Depression, Panic, GAD, OCD ++ + ++ +++ Low Sex Drive and Delayed Orgasm
Serotonin and Nor-epinephrine Reuptake Inhibitor (SNRI) Depression, Neuropathic Pain, GAD, CFS, Fibromyalgia ++ + ++ +++ Low Sex Drive and Delayed Orgasm
Bupropion (Wellbutrin) Nor-epinephrine and Dopamine Reuptake Inhibitor Depression, Smoking Cessation, ADD/ADHD ++ - - - Increased or Neutral Sex Drive
Mirtazapine (Remeron) Serotonin and Nor-epinephrine Releaser and Serotonin Receptor Blocker Depression, GAD +++ ++++ +++ - Improved Sleep, Stimulates Appetite
Trazodone (Desyrel) Serotonin Receptor Blocker Depression, Insomnia + ++++ - -- Increased Sex Drive, Improved Sleep

List of Antidepressants

Anti-Depressant Class Indications Effective Tired Weight Gain Sexual Sides Comments
Pramipexole (Mirapex) Dopamine Agonist Depression, Parkinson's, Restless Leg Syndrome ++ ++ - -- Increased Sex Drive, Gambling
Tramadol (Ultram) Serotonin and Nor-epinephrine Reuptake Inhibitor, u-Opioid Receptor Agonist Depression, Pain Killer +++ - - + Mild Delayed Orgasm, May Cause Dependence
Reboxetine (Edronax) Nor-epinephrine Reuptake Inhibitor Depression, ADD/ADHD ++ - - - None
Selegiline (Emsam) Monoamine Oxidase Inhibitor (MAOi) Depression, Parkinson's +++ - - -- Food and Drug Restrictions
Tranylcypromine (Parnate) Monoamine Oxidase Inhibitor (MAOi) Depression, Panic, Social Anxiety ++++ + + + Food and Drug Restrictions
Phenelzine (Nardil) Monoamine Oxidase Inhibitor (MAOi) Depression, Panic, Social Anxiety ++++ ++ +++ ++ Food and Drug Restrictions

When you know the list of antidepressants and their side effects up front, it makes the decision of which treatment to follow much easier. You know what to expect, and can suit your treatment to your needs.

I wish you luck with your depression, and hope you find what you're looking for.


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